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LaNts and Laminins

LaNts and Laminins

The Hamill lab blog

  • Blog
  • Science Room
    • A very friendly introduction to Basement Membranes
    • Laminins – a friendly intro!
    • LaNts – a friendly intro
    • Taking control of a cancer-associated “splicing switch”
    • LaNt alpha31 in the ocular surface; a new player in corneal wound repair?
    • LaNt alpha31 distribution in human tissues
    • Are you really as good at applying sunscreen as you think?
    • Can you replace your sunscreen with SPF containing moisturisers?
    • UV photography; how to guide
    • LaNt a31 – a breast cancer marker and potential drug target
    • Join the team
  • Core Cell and Molecular Biology + Genetics Quizzes
    • Guide to identifying mode of inheritance from genetic pedigrees
    • Cell Biology and Genetics Foundation MCQ – 1
    • Core Genetics Multiple Choice Quiz Q1
    • Genetic Pedigree Multiple Choice Quiz – 1
    • Genetic Pedigree Multiple Choice Quiz – 2
    • Genetic Pedigree Multiple Choice Quiz – 3
    • Genetic Pedigree – Multiple Choice Quiz – 4
    • Multiple Choice Quiz – Genetic Pedigrees – 5 – ABO and Rh blood group
    • Genetics Pedigrees MCQ 6 – Real Example – LOCS
    • Mitosis and Meiosis MCQ (genetics/cell biology)
    • Transcription, translation, protein and gene regulation MCQ
    • Sensitivity, Specificity and Predictive Values MCQ
    • Mean, Median, Mode MCQ
    • Hallmarks of Cancer MCQ
  • Lab Skills Quizzes
    • MCQ working in the lab
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    • MCQ Microscopy
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    • MCQ RNA/DNA techniques
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    • Science grammar quiz!
    • Lab Skill Quiz – Data interpretation I
    • Lab skills quiz – data interpretation MCQ #2
    • Lab skills MCQ – Data interpretation #3
    • Worked examples videos: basic lab calculations
  • Writing Guides
    • Downloadable Manuscript Template Doc
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    • Choosing a graph type
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  • “Life in the Lab” book
  • Experimental Design Guide
    • Statistics test – flow chart
    • Experimental Design – Part 1 – Hypotheses
    • Experimental Design – Part 2 – Measurements
    • Experimental Design – Part 3 – Controls
    • Experimental Design – part 4 – Assigning groups
    • Experimental Design – Part 5 – Sample size determination
  • MRes BLS links
    • MRes: Introduction to Lab Skills Practical Class
    • MRes – RT-PCR (video)
    • MRes – Western Blotting
    • Worked examples videos: basic lab calculations
  • The LaNts and Laminins team
  • LaNt wars: the LaNt mouse saga…

Category: science

New paper out – Laminin polymerization and inherited disease: lessons from genetics

New mini-review about laminin mutations and their effect on basement membrane assembly and tissue function.

Basement Membrane, Laminin

2 New papers out – Comprehensive reviews of conjunctival ECM and replacement strategies

“The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration” and “Biological tissues and components, and synthetic substrates for conjunctival cell transplantation” published in The Ocular Surface – links to download.

Basement Membrane, conjunctiva, disease, ECM, publication

You can see a lot by looking – fluorescence microscopy to brighten your day

Back in the lab post COVID and Dr Lee Troughton has been on the confocal microscope grabbing some cool pics … More

confocal, hemidesmosome, integrin, Laminin, microscopy

New paper out – the road to conjunctival happiness

Overview of our paper:

Mass Spectrometry Reveals α-2-HS-Glycoprotein as a Key Early Extracellular Matrix Protein for Conjunctival Cells

conjunctiva, ECM, IOVS, laminins, manuscript, Mass spectrometry, paper

New paper out – CRISPRing laminins

Attempts at genome editing laminin beta 1 with Dendra2 photoconvertible tag

Department of Eye and Vision Science, Laminin, paper

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Recent Posts

  • Outreach – Meet the Scientists at the World Museum
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  • 🧪 Life in the Lab: The Ultimate Guidebook for Aspiring Researchers – SALE NOW ON
  • They Grow Up so Fast – Congratulations to Dr Fawziah Asiri
  • Showing off microscopy images at Pint of Science

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