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LaNts and Laminins

LaNts and Laminins

The Hamill lab blog

  • Blog
  • Science Room
    • A very friendly introduction to Basement Membranes
    • Laminins – a friendly intro!
    • LaNts – a friendly intro
      • Taking control of a cancer-associated “splicing switch”
      • LaNt alpha31 in the ocular surface; a new player in corneal wound repair?
      • LaNt alpha31 distribution in human tissues
      • LaNt wars: the LaNt mouse saga…
      • LaNt a31 – a breast cancer marker and potential drug target
    • Developing A New Therapy for Aniridia
    • Are you really as good at applying sunscreen as you think?
      • Can you replace your sunscreen with SPF containing moisturisers?
      • UV photography; how to guide
    • Join the team
  • Core Cell and Molecular Biology + Genetics Quizzes
    • Guide to identifying mode of inheritance from genetic pedigrees
    • Cell Biology and Genetics Foundation MCQ – 1
    • Core Genetics Multiple Choice Quiz Q1
    • Genetic Pedigree Multiple Choice Quiz – 1
    • Genetic Pedigree Multiple Choice Quiz – 2
    • Genetic Pedigree Multiple Choice Quiz – 3
    • Genetic Pedigree – Multiple Choice Quiz – 4
    • Multiple Choice Quiz – Genetic Pedigrees – 5 – ABO and Rh blood group
    • Genetics Pedigrees MCQ 6 – Real Example – LOCS
    • Mitosis and Meiosis MCQ (genetics/cell biology)
    • Transcription, translation, protein and gene regulation MCQ
    • Sensitivity, Specificity and Predictive Values MCQ
    • Mean, Median, Mode MCQ
    • Hallmarks of Cancer MCQ
  • Lab Skills Quizzes
    • MCQ working in the lab
    • MCQ – Lab calculations
    • MCQ Microscopy
    • MCQ protein work
    • MCQ cell culture
    • MCQ RNA/DNA techniques
    • MCQ Flow cytometry and FACS
    • Science grammar quiz!
    • Lab Skill Quiz – Data interpretation I
    • Lab skills quiz – data interpretation MCQ #2
    • Lab skills MCQ – Data interpretation #3
    • Worked examples videos: basic lab calculations
  • Writing Guides
    • Downloadable Manuscript Template Doc
    • Titles
    • Preparing Scientific Posters
    • Abstracts
    • Introductions
    • Materials and Methods
    • Results Figure Preparation
    • Choosing a graph type
    • Figure legends
    • Results
    • Discussions
    • Quick tips-methods
    • Quick tips-results
  • “Life in the Lab” book
  • Experimental Design Guide
    • Statistics test – flow chart
    • Experimental Design – Part 1 – Hypotheses
    • Experimental Design – Part 2 – Measurements
    • Experimental Design – Part 3 – Controls
    • Experimental Design – part 4 – Assigning groups
    • Experimental Design – Part 5 – Sample size determination
  • MRes BLS links
    • MRes: Introduction to Lab Skills Practical Class
    • MRes – RT-PCR (video)
    • MRes – Western Blotting
    • Worked examples videos: basic lab calculations

Lab trip

 

You can see a lot by looking – confocal microscopy imaging of laminins (etc)

Science and art meet when imaging laminins and other ecm proteins using confocal microscopy

art, Basement Membrane, ECM, imaging, Laminin

Troubles with -seq data

Hypothesis independent screens are really powerful but with great power comes great responsibility. While every gene, miRNa, or protein might…

lab meeting, Life in the laminin lab, miRNA, powerpoint, RNAseq

Bringing my molecular biology research into the real world – Aniridia Network UK meeting

by Thanos P. Last week I was invited to take part in the annual conference of Aniridia Network UK. There,…

Setting the Benchmarks for Keratoconus Treatments

Our newest paper has just been published in the Journal of Refractive Surgery (available here – open access). In it…

Lamin-in

Laminins are extracellular proteins, lamins are nuclear envelope proteins – similar names, very different jobs! Want to learn about laminins?…

cone of shame, Laminin, Life in the laminin lab

Motivational tactics

Four stars

 

Laminin Research Highlights – what a difference a beta chain makes

#2 of our laminin highlights series. This time I want to draw  attention to two papers, both from March this…

Interviewing Confidence

Continuing our Conro’s PhD interview series… see other two here New Interviewing Techniques and Interviewing techniques

interview, interview questions, interview technique, Life in the laminin lab

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Recent Posts

  • Funded PhD position Available – Laminins, Superresolution microscopy and Junctional Epidermolysis Bullosa
  • Zooming in on laminin 332 – public seminar for ER research organisation
  • New Paper Published – Understanding Laminin N Terminus Alpha 31’s Role in Corneal Healing
  • Outreach – Meet the Scientists at the World Museum
  • They grow up so fast – Dzhalil + Louie at ILCAMS day

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Lab Life

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Experiment overview
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Drs Hamill, Iorio and Sheridan
Drs Hamill, Iorio and Sheridan
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Ronnald and his mices
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Hemidesmosome EM
Filming for lab skills teaching
Filming for lab skills teaching
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human AS - stem cells + LaNt

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